Apoptosis Research Repository

Explore the latest studies, experimental protocols, and scientific breakthroughs in apoptosis mechanisms

Research Articles

How a Natural Ginseng Compound Is Revolutionizing Cancer Therapy: The Ginsenoside Rp1 Story

Discover how Ginsenoside Rp1 enhances anti-cancer effects of Actinomycin D by targeting the AKT-SIRT1 pathway to overcome drug resistance in cancer treatment.

Addison Parker
Nov 02, 2025

Disarming Cancer: How a Tiny Peptide from HIV Fights Aggressive Tumors

Discover how SMR peptide derived from HIV targets mortalin to fight cancer through multiple mechanisms including disrupting extracellular vesicles and restoring immune recognition.

Isaac Henderson
Oct 31, 2025

Cell Cycle Checkpoints: The Body's Anti-Cancer Defense System and How We Can Weaponize It

Explore how cell cycle checkpoints serve as the body's defense against cancer and how modern medicine is weaponizing these mechanisms to develop targeted anticancer therapies.

Christopher Bailey
Oct 29, 2025

The Sequence Secret: How Drug Order Turns Cancer Treatment Into a Precision Strike

Discover how the sequence of administering paclitaxel and cisplatin dramatically impacts cancer treatment efficacy and safety in this scientific exploration.

Isaac Henderson
Oct 25, 2025

A Cellular Saboteur: How a New Drug Tricks Cancer Cells into Self-Destructing

Discover how DPQZ, a novel antitubulin agent, induces apoptosis in oral cancer cells through Ras/Raf inhibition and MAPK activation.

Chloe Mitchell
Oct 23, 2025

BR101801: A Triple-Target Therapy Revolutionizing the Fight Against Advanced Blood Cancers

Explore BR101801, a novel triple-inhibitor therapy targeting PI3Kγ, PI3Kδ, and DNA-PK for advanced hematologic malignancies. Learn about preclinical insights and clinical trial results.

Ethan Sanders
Oct 22, 2025

Breaking the Shield: How Targeting a Cellular "Workaholic" Protein Could Revolutionize Cancer Therapy

Explore how CK2 inhibitors like BMS-595 are reshaping cancer therapy by targeting tumor addiction pathways and modulating the immune microenvironment.

Aubrey Brooks
Oct 19, 2025

A One-Two Punch: New Combo Therapy Delivers a Knockout Blow to a Vicious Leukemia

Discover how combining FLT-3 inhibitors with HSP90 blockers creates a synergistic therapy that effectively targets acute myelogenous leukemia with mutant FLT-3.

Naomi Price
Oct 10, 2025

Breaking Down Cancer's Defenses: How Dual-Pronged Inhibitors Make Tumors More Vulnerable to Radiation Therapy

Explore how NVP-BEZ235 and NVP-BGT226 dual inhibitors enhance tumor radiosensitivity by targeting the PI3K/Akt/mTOR pathway in cancer treatment.

Aurora Long
Oct 06, 2025

Golden Bullets: How pH-Sensitive Gold Nanorods Are Revolutionizing Lung Cancer Therapy

Discover how pH-sensitive gold nanorods with transferrin targeting are revolutionizing lung cancer therapy by delivering doxorubicin precisely to cancer cells while minimizing side effects.

Aubrey Brooks
Aug 23, 2025

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